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Category Archives: Action Potential Models
2023-2025 Postdoctoral Research Fellow positions available in our team (vacancies closed)
N.B. Applications now closed. We are looking for new members to join our Wellcome-funded team of cardiac electrophysiology modellers, to develop mathematical models of ion channel currents and cardiac cells for assessing the safety of new pharmaceutical drugs. You’ll be … Continue reading
Postdoctoral Research Fellow positions available in our team (recruitment now closed)
We are looking for new members to join a Wellcome-funded team of cardiac electrophysiology modellers, to develop mathematical models of ion channel currents and cardiac cells for assessing the safety of new pharmaceutical drugs. Continue reading
2021 CiPA in-silico Modelling Workshop
Abstract submission for the 2021 CiPA in-silico modelling meeting is open now. Continue reading
Our new review on fitting cardiac models
A reasonably short post to let you know about our recently published paper in WIREs Systems Biology and Medicine on parameter fitting in cardiac ion channel and action potential models with David Christini. There is an accessible introductory news article … Continue reading
Job Available: Statistical inference for mechanistic models
N.B. Applications for this position are now closed. We are offering a 3 year position as a research fellow in statistical inference for mechanistic models. This is offered at either Postdoc or Senior postdoc level (equivalent grade to Assistant Professor) … Continue reading
Posted in Action Potential Models, Drug action, Experimental Design, Ion Channel Models, Model Development, Numerics, Stats and Inference
Tagged Bayesian Inference, calibration, identifiability, inference, inverse problem, job, jobs, model complexity, model construction, model discrepancy, model selection, parameter fitting, validation
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Job Available: Research Software Engineer
Edit: please note the deadline for applications has now passed. Here’s a great opportunity to join our team at the University of Nottingham on a 5 year Research Software Engineering (RSE) position: https://www.nottingham.ac.uk/jobs/currentvacancies/ref/IS046219 The deadline for applications is 3rd March … Continue reading
Postdoctoral Research Positions Available
N.B. 16th Jan 2019 – the applications for these positions are now closed. This post is to let people know about some opportunities for postdoctoral research here in the Centre for Mathematical Medicine & Biology, based in Mathematical Sciences, University … Continue reading
Numerical errors from ODE solvers can mess up optimisation and inference very easily
(Subtitle: “when you’ve got a lot of data points!”) This post is for people interested in doing optimisation or inference with Differential Equation (DE) models. If you are a statistician, you might be used to treating model simulators as black … Continue reading
A report on the Toronto CiPA in-silico modelling workshop
This is a follow-up to this post advertising the workshop. On the 9th November 2017 the CiPA in-silico Working Group hosted a meeting in Toronto General Hospital that the Cardiac Physiome meeting kindly let us run as a satellite meeting … Continue reading
CiPA in-silico modelling meeting
There’s an effort underway to evaluate, improve and implement mathematical models of cardiac electrophysiology for pharmaceutical cardiac safety testing and regulatory practice. In particular, to be part of a more mechanistic and accurate in-vitro assessment of pro-arrhythmic risk than the … Continue reading