
Recent Posts
Archived posts
Tag cloud
ablation Action potential alpine cyclamen APD Bayesian benchmark bidomain block calibration Cardiac electrophysiology CellML CiPA concentrationeffect conductances connexin curation disease doseresponse drug Drug action Drug safety ECG Finite element finite element meshes finite element simulations Functional Curation Future gap junctions Hypothesis IC50 identifiability inference initial conditions inverse problem ion channel ion current job logistic log logistic Meshing model model comparison model complexity model construction Models model selection monodomain mouse New Paper ODE solving open questions opinion parameter fitting pIC50 QT safety Safety pharmacology scar screening SEDML sensitivity sensitivity analysis Silly simulation standing wave steady state tetrahedral mesh tetrahedral meshes tissue simulation training uncertainty validation Virtual experiments wave Web LabCategories
Follow me on Twitter
My TweetsBlog Stats
 7,802 hits
RSS Feeds
Wordpress Links
Tag Archives: model construction
Ablation, scars and insights from parameter lumping
This is quite a long post elaborating on a bit of work I’ve been doing with Greg Morley and his group, which was published in Scientific Reports. I hope it provides an accessible introduction to a fairly complicated set of experiments … Continue reading
Is your model really ‘comprehensive’?
I’ve noticed more and more papers using the phrase “comprehensive model”. This phrase grates every time, and this post is about why. I thought this might just be me getting old and grumpy, so I plotted the mentions of the … Continue reading
Posted in Blog, Model Development, Silly
Tagged model comparison, model construction, Models, opinion, Silly, validation
Leave a comment
Job Advert
A quick shameless plug for a job we are advertising. This is a 3 year postdoctoral position to work with me in the Computational Biology Group in the Department of Computer Science, University of Oxford. It would best suit someone … Continue reading
Posted in Future developments
Tagged inference, inverse problem, job, model comparison, model construction, parameter fitting, uncertainty
Leave a comment
Hypotheses on hypotheses on …
(Subtitle: building on foundations of unknown shakiness?) In a lot of fields, a new mathematical model is constructed for each problem, and the model is an encoding of the quantitative rules of the hypothesis you are testing. The model is … Continue reading