Tag Archives: simulation

Job Available: Research Software Engineer

Posted on February 11, 2019 by Gary Mirams

Edit: please note the deadline for applications has now passed. Here’s a great opportunity to join our team at the University of Nottingham on a 5 year Research Software Engineering (RSE) position: https://www.nottingham.ac.uk/jobs/currentvacancies/ref/IS046219 The deadline for applications is 3rd March … Continue reading →

Posted in Action Potential Models, Drug action, Future developments, Ion Channel Models, Model Development, Numerics, Safety Pharmacology, Stats and Inference | Tagged , , , , , , , , | Leave a comment

Numerical errors from ODE solvers can mess up optimisation and inference very easily

Posted on October 17, 2018 by Gary Mirams

(Subtitle: “when you’ve got a lot of data points!”) This post is for people interested in doing optimisation or inference with Differential Equation (DE) models. If you are a statistician, you might be used to treating model simulators as black … Continue reading →

Posted in Action Potential Models, Numerics, Stats and Inference | Tagged , , , , , , , | 7 Comments

Ablation, scars and insights from parameter lumping

Posted on August 4, 2016 by Gary Mirams

This is quite a long post elaborating on a bit of work I’ve been doing with Greg Morley and his group, which was published in Scientific Reports. I hope it provides an accessible introduction to a fairly complicated set of experiments … Continue reading →

Posted in Action Potential Models, Future developments, Model Development, Tissue Simulations | Tagged , , , , , , , , , , | Leave a comment

In-silico Action Potential Prediction Web Portal

Posted on July 23, 2014 by Gary Mirams

This post is to announce that we are making our in-silico action potential prediction web portal (AP-predict) available for public use. The portal is free, you just need to register for an account. We’d be happy to have any feedback on … Continue reading →

Posted in Action Potential Models, Drug action, Safety Pharmacology | Tagged , , , , , , , | Leave a comment

Quick and easy meshing…

Posted on January 8, 2014 by Gary Mirams

I have never come across any (free) 3D meshing software that is really quick and easy to use that creates reliable tetrahedral meshes. If you have, then please let me know in the comments! DistMesh The nearest thing I have … Continue reading →

Posted in Tissue Simulations | Tagged , , , , , , | 3 Comments