Tag Archives: hERG

Three potassium channel modelling papers

Just a quick note to tell you about our latest batch of papers in the “Heart By Numbers” special issue of Biophysical Journal which arose from a meeting in Berlin last year. They are all about IKr, the rapid-delayed rectifying … Continue reading

Posted in Experimental Design, Future developments, Ion Channel Models, Model Development, Numerics, Stats and Inference | Tagged , , , , , , , , , , , | 1 Comment

A report on the Toronto CiPA in-silico modelling workshop

This is a long-awaited follow-up to this post advertising the workshop. Apologies it has taken so long, the fact I wanted to write something about the next meeting, which we just had, reminded me I never posted all these talks. … Continue reading

Posted in Action Potential Models, Drug action, Future developments, Ion Channel Models, Model Development, Safety Pharmacology | Tagged , , , , , , , | 1 Comment

Short and rich voltage-clamp protocols

This is a quick post to tell you all about Kylie’s new paper on sinusoidal-wave based voltage clamp protocols that has been published in the Journal of Physiology, and there’s an associated commentary from Ele Grandi. In the paper, some … Continue reading

Posted in Experimental Design, Future developments, Ion Channel Models, Model Development, Stats and Inference | Tagged , , , , , , , , , , , , | 6 Comments