-
Recent Posts
- 2024-2025 Postdoctoral Research Positions – Applications closed
- New textbook chapter – Modelling Drug Induced Proarrhythmic Risk and a challenge for whole-heart computational modellers
- 2023-2025 Postdoctoral Research Fellow positions available in our team (vacancies closed)
- Englishman in New York (travel tips for Brits in the USA)
- Postdoctoral Research Fellow positions available in our team (recruitment now closed)
Archived posts
Tag cloud
- ablation
- Action potential
- alpine cyclamen
- APD
- Bayesian Inference
- benchmark
- bidomain
- block
- calibration
- Cardiac electrophysiology
- CellML
- CiPA
- concentration-effect
- conductances
- curation
- dose-response
- drug
- Drug action
- Drug safety
- ECG
- Finite element
- finite element meshes
- finite element simulations
- Functional Curation
- Future
- hERG
- high-throughput
- Hypothesis
- IC50
- identifiability
- IKr
- inference
- initial conditions
- inverse problem
- ion channel
- ion current
- job
- jobs
- logistic
- log logistic
- Meshing
- model
- model comparison
- model complexity
- model construction
- Models
- model selection
- mouse
- numerical methods
- ODE solving
- open questions
- opinion
- parameter fitting
- pIC50
- QT
- Safety pharmacology
- scar
- screening
- SED-ML
- sensitivity
- sensitivity analysis
- Silly
- simulation
- standing wave
- steady state
- tetrahedral mesh
- tetrahedral meshes
- tissue simulation
- Torsade
- training
- uncertainty
- validation
- Virtual experiments
- wave
- Web Lab
Categories
Follow me on Twitter
My TweetsBlog Stats
- 32,759 hits
RSS Feeds
-
Join 627 other subscribers
Wordpress Links
Category Archives: Unexplained
New textbook chapter – Modelling Drug Induced Proarrhythmic Risk and a challenge for whole-heart computational modellers
A little note to say that a textbook chapter I wrote last year is now online and available as part of the Springer Reference work “Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays“ The chapter is available here, and if … Continue reading
A standing cardiac electrical wave…?
Here’s my first post on an unexplained result. Normally at a ‘steady pacing’ rate cardiac tissue will recover enough to let the next wave through. But there’s a maximum rate you can achieve: if you try to pace faster than … Continue reading
Posted in Action Potential Models, Tissue Simulations, Unexplained
Tagged bidomain, Finite element, mouse, standing wave, tissue simulation, wave
1 Comment
Mathematical Matters of the Heart 