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Category Archives: Experimental Design
2023-2025 Postdoctoral Research Fellow positions available in our team (vacancies closed)
N.B. Applications now closed. We are looking for new members to join our Wellcome-funded team of cardiac electrophysiology modellers, to develop mathematical models of ion channel currents and cardiac cells for assessing the safety of new pharmaceutical drugs. You’ll be … Continue reading
Our new review on fitting cardiac models
A reasonably short post to let you know about our recently published paper in WIREs Systems Biology and Medicine on parameter fitting in cardiac ion channel and action potential models with David Christini. There is an accessible introductory news article … Continue reading
Job Available: Statistical inference for mechanistic models
N.B. Applications for this position are now closed. We are offering a 3 year position as a research fellow in statistical inference for mechanistic models. This is offered at either Postdoc or Senior postdoc level (equivalent grade to Assistant Professor) … Continue reading
Posted in Action Potential Models, Drug action, Experimental Design, Ion Channel Models, Model Development, Numerics, Stats and Inference
Tagged Bayesian Inference, calibration, identifiability, inference, inverse problem, job, jobs, model complexity, model construction, model discrepancy, model selection, parameter fitting, validation
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Three potassium channel modelling papers
Just a quick note to tell you about our latest batch of papers in the “Heart By Numbers” special issue of Biophysical Journal which arose from a meeting in Berlin last year. They are all about IKr, the rapid-delayed rectifying … Continue reading
Postdoctoral Research Positions Available
N.B. 16th Jan 2019 – the applications for these positions are now closed. This post is to let people know about some opportunities for postdoctoral research here in the Centre for Mathematical Medicine & Biology, based in Mathematical Sciences, University … Continue reading
Short and rich voltage-clamp protocols
This is a quick post to tell you all about Kylie’s new paper on sinusoidal-wave based voltage clamp protocols that has been published in the Journal of Physiology, and there’s an associated commentary from Ele Grandi. In the paper, some … Continue reading
Posted in Experimental Design, Future developments, Ion Channel Models, Model Development, Stats and Inference
Tagged Bayesian Inference, Cardiac electrophysiology, hERG, identifiability, IKr, inference, inverse problem, ion channel, model, model construction, parameter fitting, parameterisation, validation
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Postdoc position available
N.B. This position is now closed. Another short post, just to advertise a postdoctoral research associate (PDRA) position available to work with me. It’s a two year position, based at the Centre for Mathematical Medicine & Biology at the University … Continue reading