Tag Archives: tissue simulation

Ablation, scars and insights from parameter lumping

Posted on August 4, 2016 by Gary Mirams

This is quite a long post elaborating on a bit of work I’ve been doing with Greg Morley and his group, which was published in Scientific Reports. I hope it provides an accessible introduction to a fairly complicated set of experiments … Continue reading →

Posted in Action Potential Models, Future developments, Model Development, Tissue Simulations | Tagged , , , , , , , , , , | Leave a comment

Action potential durations and QT intervals

Posted on March 21, 2014 by Gary Mirams

Here’s an interesting little result that is thanks to Kylie. She found it whilst doing the work for her paper on prediction of drug compound effects at the tissue scale using data on multiple ion channel block. But we didn’t … Continue reading →

Posted in Action Potential Models, Drug action, Tissue Simulations | Tagged , , , , , , | 7 Comments

A standing cardiac electrical wave…?

Posted on January 28, 2014 by Gary Mirams

Here’s my first post on an unexplained result. Normally at a ‘steady pacing’ rate cardiac tissue will recover enough to let the next wave through. But there’s a maximum rate you can achieve: if you try to pace faster than … Continue reading →

Posted in Action Potential Models, Tissue Simulations, Unexplained | Tagged , , , , , | 1 Comment